Key Protein Revealed As Trigger For Stem Cell Development

A natural trigger that enables stem cells to become any cell-type in the body has been discovered by scientists.

Researchers have identified a protein that kick-starts the process by which stem cells can develop into different cells in the body, for instance liver or brain cells.

Their discovery could help scientists improve techniques enabling them to turn stem cells into other cell types in the laboratory. These could then be used to test drugs or help create therapies for degenerative conditions such as Parkinson’s diseasemotor neurone disease,multiple sclerosis and liver disease.

Scientists from the Medical Research Council Centre for Regenerative Medicine at the University of Edinburgh, who studied embryonic stem cells in mice, also developed a technique enabling them to highlight the presence of the key protein – Tcf15 – in the cells.

This means that researchers can identify which cells have the protein and watch how it affects stem cells in real time to gain a better understanding of how it works.

The study, published in the journal Cell Reports, was funded by the Wellcome Trust and the Biotechnology and Biological Sciences Research Council,

Dr Sally Lowell, from the MRC Centre for Regenerative Medicine at the University of Edinburgh, said: “This gives us better insight into the crucially important first step stem cells take to differentiate into other cell types. Understanding how and when this happens could help to improve the way in which we are able to control this process.”

Researchers pinpointed the protein by looking at how some stem cells are naturally prevented from specialising into other cell types.

They found two sets of proteins, one of which binds to the other blocking them from carrying out their various functions.

They were then able to screen the blocked proteins to find out which ones would enable stem cells to differentiate.

34 pensamientos en “Key Protein Revealed As Trigger For Stem Cell Development”

  1. Greetings I am so delighted I found your blog page, I really
    found you by error, while I was looking on Aol for something else, Nonetheless I am
    here now and would just like to say cheers for a remarkable post
    and a all round thrilling blog (I also love the theme/design), I don’t have time to browse it all at the moment but I have book-marked it and also included your RSS
    feeds, so when I have time I will be back to read a
    lot more, Please do keep up the awesome b.

    1. Thank you very much for reading. I am delighted with the reception they are getting the blog.Me glad I can be useful information for word.Intentaré keep it updated.
      Thanks, I hope to reach as many people as possible.
      Jesus Santiago.

    1. I’m glad that the information may be true for their students. If you need any additional specialized information, feel free to ask me.
      I’ll try to answer best.
      Currently working as a physician and university professor. We discussed much my students and me about these issues.
      Thank you very much for writing.
      A greeting.
      Jesus Santiago.

  2. Hi this is kind of of off topic but I was wanting to know if blogs
    use WYSIWYG editors or if you have to manually code with HTML.

    I’m starting a blog soon but have no coding experience so I wanted to get guidance from someone with experience. Any help would be greatly appreciated!

    1. Hi, I have no programming experience. The blog is made ​​through a wordpress template, where and added some wiges in HTLM with own text command downloaded from internet to customize the blog page .

      Sorry I can not help more.This is the first blog that I do.

      Thank you very much for writing

      A hug.

      Jesçus Santiago

  3. Hi there, just became alert to your blog through Google, and
    found that it is truly informative. I’m going to watch out for brussels. I’ll appreciate if you
    continue this in future. Numerous people will be benefited from your writing.
    Cheers!

  4. Just wish to say your article is as amazing. The clearness
    in your submit is just cool and that i can suppose you’re an expert in this subject. Well along with your permission allow me to snatch your feed to stay up to date with imminent post. Thank you a million and please keep up the gratifying work.

    1. Hi, thanks for your comment. I’m no expert in the field, working as director of a hospital in Spain and I am in Portugal University professor giving a degree in nursing. My interest in multiple sclerosis is because for 25 years study progress by having a sibling with the disease. I try to move that I consider interesting news to stay current on advances that occur.

      Thanks for writing.

      Jesus Santiago.

  5. Woah! I’m really enjoying the template/theme of this website. It’s simple,
    yet effective. A lot of times it’s challenging to get that “perfect balance” between superb usability and appearance. I must say you have done a amazing job with this. In addition, the blog loads very quick for me on Safari. Exceptional Blog!

    1. Hello, I’m glad you like the blog. It’s simple and I’m sure is much improved in the future, but my programming limitations are evident.
      As for the burden of blog I am very satisfied because I did tests with different browsers before creating it are very good (just load 6-10 milliseconds). It’s an issue that’s important to me.

      Thank you very much for writing.

      A hug.

      Jesus Santiago.

    1. Thank you very much for your opinion.Espero that it remains useful blog for everyone.
      I invite you to visit my new blog,Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

      Thanks for writing.

    1. Thank you very much for your opinion.Espero that it remains useful blog for everyone.
      I invite you to visit my new blog,Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

      Thanks for writing.

  6. We stumbled over here coming from a different website and thought I may as well check things out.
    I like what I see so now i’m following you. Look forward to finding out about your web page repeatedly.

    1. Thank you very much for your advice.
      I invite you to visit my new blog,Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

      Thanks for writing.

    1. Thank you very much for your comment. Take this opportunity to tell you,Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

      Thank you for reading.

  7. Greetings, I think your web site could possibly be having browser compatibility problems.
    Whenever I look at your website in Safari, it looks fine
    however when opening in Internet Explorer, it’s got some overlapping issues. I just wanted to provide you with a quick heads up! Besides that, excellent website!

    1. Thank you very much for your comment. I have checked the navigation in chrome, firefox and internet explorer and load perfectly. I do not have to check safari.

      Thank you for your notice.

      Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

  8. You really make it seem so easy together with your presentation however I to find this matter to be
    actually something which I believe I’d by no means understand. It kind of feels too complicated and extremely broad for me. I am looking ahead in your next post, I’ll attempt to get the hang of it!

    1. Thank you very much for your comment. Take this opportunity to tell you,Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

      Thank you for reading.

    1. Thank you very much for your comment. Take this opportunity to tell you,Because I had to change the housing of the Blog, you can follow the updates on the new blog I’ve created: http://blogesclerosismultiple.com/ You will have all old news, as well as the all commentary and old files at your disposal in the new blog. Thank you very much and forgive the inconvenience that you may cause. See you in http://blogesclerosismultiple.com/.

      Thank you for reading.

Responder

Por favor, inicia sesión con uno de estos métodos para publicar tu comentario:

Logo de WordPress.com

Estás comentando usando tu cuenta de WordPress.com. Cerrar sesión / Cambiar )

Imagen de Twitter

Estás comentando usando tu cuenta de Twitter. Cerrar sesión / Cambiar )

Foto de Facebook

Estás comentando usando tu cuenta de Facebook. Cerrar sesión / Cambiar )

Google+ photo

Estás comentando usando tu cuenta de Google+. Cerrar sesión / Cambiar )

Conectando a %s