Rebif (interferon beta-1a) has been approved by the FDA for the treatment of relapsing forms of multiple sclerosis. Rebif has been shown to decrease the frequency of clinical exacerbations and delay the accumulation of physical disability in patients with MS. The recommended dose of the product is 44 mcg three times per week to be administered by subcutaneous injection. Rebif is supplied in single-use, pre-filled syringes.
Rebif previously was approved in Europe in 1998 and currently is registered for use in over 70 countries.